LSD long-term effects

LSD (Lysergic acid diethylamide) is a potent hallucinogen that can significantly affect visual, auditory, and emotional perceptions. Although it is rarely physically addictive, the psychological long-term effects should not be underestimated.

What happens in the body?

Physically, long-term effects of LSD are rare, yet the following effects may occur:

• Increased blood pressure and pulse
• Temperature fluctuations
• Occasional stomach discomfort
• Possible neurological changes with prolonged use

LSD and mental health

The greatest danger lies in the psychological realm. Repeated LSD use can promote or exacerbate mental illnesses. Most commonly occurring are:

• HPPD (persistent perceptual disturbances)
• Anxiety and paranoia
• Exacerbation of existing mental disorders such as schizophrenia

Impact on the brain

LSD affects the brain's serotonergic system. Regular use can impair cognitive functions, such as:

• Reduced concentration
• Memory gaps
• Altered perception of space, time, and reality

Addiction risk with LSD

Physical dependence does not occur with LSD, but psychological dependence can develop. The experience is perceived as so impressive that some may want to repeat it—at the risk of losing control.

Psychoses as a possible long-term effect

Those with a genetic predisposition or mental health issues should avoid LSD. In such cases, it can lead to persistent psychoses—with delusions, loss of reality, and ongoing confusion.

Compared to other hallucinogens

Substances like psilocybin (magic mushrooms) or DMT can also have long-term effects. However, LSD often exhibits particularly strong and long-lasting effects, which can be problematic with frequent use.

Conclusion

Even though LSD does not appear to cause physical dependence at first glance, the long-term effects should not be underestimated. Particularly, psychological and cognitive effects can be significant. Anyone who uses or intends to use LSD should do so with great caution and be well-informed beforehand.