Poisonous lettuce: effects, use, and risks at a glance

Prickly Lettuce: Effects, Uses, and Risks at a Glance

Niklas Bergmann, M.A.

biochemist and scientific author

Inhaltsverzeichnis: Poisonous lettuce: effects, use, and risks at a glance

The name initially sounds off-putting: Giftlattich. One immediately thinks of something best not touched, let alone consumed. However, upon closer examination of this plant, it quickly becomes apparent: The name is somewhat dramatic – and the herb itself is far more intriguing than one might expect.

Giftlattich – botanically known as Lactuca virosa – is a wild plant with history. It was used as a remedy in ancient Greece, and it frequently appears in old herbal books of the Middle Ages: as a natural painkiller, as a sedative, and even as a herbal alternative to opium.

Today, Giftlattich leads a niche existence – somewhere between naturopathy, the online herb scene, and urban myth status. But this is precisely what makes it so interesting: Those who understand it discover a piece of almost forgotten plant knowledge – with potential, but also with limitations.

What exactly is Giftlattich – and where does it grow?

Giftlattich belongs to the genus of lettuces – the same family as our everyday lettuce (Lactuca sativa). However, Lactuca virosa, the wild brother, is of a completely different caliber. It grows unnoticed along roadsides, railway embankments, on wastelands, or at the edges of forests. It particularly thrives in nutrient-rich, slightly disturbed soils – places where hardly anyone looks.

The plant can grow surprisingly large – up to two meters high, with thick, spiky leaves and a strong taproot. The most noticeable difference from other wild herbs is its milky sap: When the stem or a leaf is cut, a whitish, slightly sticky sap emerges – and it is this sap that contains the substances that give Giftlattich its effects.

Anyone thinking of poisonous plants like monkshood or deadly nightshade is mistaken. Giftlattich is not acutely toxic, at least not in small quantities – but it does have effects, specifically on the central nervous system. Hence the name: not deadly, but also not a herbal tea for casual consumption.

Recognizing Giftlattich: This is what the wild plant looks like

For those who want to venture out on their own: Recognizing wild lettuce is not rocket science, but it does require a bit of practice. At first glance, it doesn't look spectacular. Many confuse it with thistles, wild lettuce, or even young plants of ragwort.

Here are the most important identifying features:

  • Height: up to 2 m tall
  • Stem: sturdy, often reddish-violet in color, with small spines on the underside
  • Leaves: elongated, serrated, also with spines on the underside of the midrib
  • Milky sap: oozes when stems or leaves are broken – whitish, bitter, and slightly sticky
  • Flowers: yellowish, inconspicuous, similar to dandelions – but smaller

Practical tip: The typical, slightly resinous smell and the mildly calming effects of the milky sap when drying are often the best indication that you have the right candidate in front of you.

Wild Lettuce Effects: What Lies Behind the Myth?

The effects of wild lettuce are what make it so legendary – and at the same time so controversial. It was once called "wild opium lettuce." That sounds dramatic – but it has a kernel of truth.

The milky sap of the lettuce contains the compounds Lactucin and Lactucopicrin – both are known as sesquiterpene lactones. They have mild pain-relieving, antispasmodic, and most importantly: calming effects.

Historically, the dried sap, also known as "Lactucarium," was used as a natural sleep aid – for restlessness, cough, or nervous agitation. Particularly intriguing: Some people report a dreamy, almost psychedelic state after consumption, especially at higher doses.

But caution: The effects vary greatly among individuals – and depending on preparation, dosage, and sensitivity, they can range from gentle to intense. Side effects such as drowsiness, headaches, or stomach discomfort are possible – so it's not an everyday herb for everyone.

Wild Lettuce: Effects, Uses, and Risks Overview

Wild Lettuce Tea & Extracts: Application, Effects, and Risks

Those who approach wild lettuce usually do so through a tea made from the dried leaves. It tastes bitter, vaguely reminiscent of wormwood or valerian – and has (with appropriate quality and quantity) mildly calming and relaxing effects.

Here's how:

Tea Preparation (classic):

  • 1–2 teaspoons of dried, crushed leaves
  • pour over 250 ml of hot water
  • let steep for 10–15 minutes
  • do not sweeten – otherwise, the bitter taste is masked (which is part of the effects)

Extracts and tinctures from the milky sap are significantly more potent but also harder to dose. Some experiment with thickened lactucarium – the dried sap – which they process into resin or drops. Such preparations are sometimes available in specialized online shops – often without clear dosage instructions.

Important: Wild lettuce is not an officially recognized medicine. Those who use it do so at their own risk – and should read up thoroughly or seek medical advice. For pregnant women, nursing mothers, or people with liver problems, the tea is not recommended.

Buying Wild Lettuce: Between Pharmacy Secret Tip and Niche Product

Wild lettuce is not a shelf product. You will rarely find it in regular pharmacies – at least not openly in the window. However, it is available in specialized herbal stores, online shops, or through small providers from the naturopathy scene.

When purchasing, pay attention to:

  • Plant part: dried leaves or resin?
  • Origin: preferably organic or wild collection from Europe
  • Processing: gently dried, no additives
  • Packaging: lightproof, aroma-protected – to preserve the active ingredients

The price can vary greatly depending on quality – some providers charge significantly more for lactucarium or extracts than the degree of effectiveness justifies. Those experienced with herbs might also consider collecting and drying the lettuce themselves – provided they are well-versed in plant knowledge.

Conclusion: An Underestimated Herb – To Be Used with Caution

Wild lettuce is an herb with history – and with character. It is not the new CBD, not the legal LSD, and not a miracle cure from nature. But it is a piece of old healing knowledge that is slowly being rediscovered – by people who read between the lines of herbal books.

Anyone who seriously engages with the plant quickly realizes: There is potential in it. Especially for people with sleep problems, restlessness, or a penchant for self-experimentation.

But – and this is important – wild lettuce demands respect. It is not a toy, not a party herb, and not a tea for every evening. Those who use it should know what they are doing – and treat it as what it is: a strong, old natural remedy with effects.


Niklas Bergmann, Fachautor

Freut euch auf die Insights von unserem Biochemiker Niklas Bergmann! Mit seinem tiefen Verständnis für alles, was mit Hanf zu tun hat, liefert er euch die neuesten und coolsten Infos direkt in euer Feed. Schnörkellos und klar verpackt er das komplexe Thema Cannabinoide und macht es für euch easy zugänglich. Mit Niklas an der Spitze unseres Wissens-Teams seid ihr immer top informiert.

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